We are sharing this information so you’ll know what to expect from the process of preparing a Novoeight® dose. For full instructions, refer to the FDA-approved patient information and Instructions for Use.

Preparing an infusion.

First, you’ll need to reconstitute Novoeight®, which comes in powder form. “Reconstitute” means mixing it with diluent to create a liquid. MixPro® is a prefilled syringe that comes with every package of Novoeight®.

Choose a place where you can prepare your dose on a level surface and gather everything you’ll need:

  • A clean surface
  • Alcohol swabs
  • Novoeight® vial, in your doctor’s recommended dose
  • MixPro® prefilled syringe with diluent
  • Vial adapter
  • Plunger rod

With MixPro®, preparing an infusion is fast: just attach, twist, and mix.

The prefilled syringe means no extra steps to fill a syringe with diluent.


Please note, this is not the complete Novoeight® Instructions for Use. Please refer to the Instructions for Use provided with the Prescribing Information.

Selected Important Safety Information

You should not use Novoeight® if you are allergic to factor VIII or any of the other ingredients of Novoeight® or if you are allergic to hamster proteins.

Call your healthcare provider right away and stop treatment if you get any of the following signs of an allergic reaction: rashes or hives, difficulty breathing or swallowing, tightness of the chest, swelling of the lips and tongue, light-headedness, dizziness or loss of consciousness, pale and cold skin, fast heartbeat, or red or swollen face or hands.

Indications and Usage

Novoeight® (Antihemophilic Factor [Recombinant]) is an injectable medicine used to control and prevent bleeding in people with hemophilia A. Your healthcare provider may give you Novoeight® when you have surgery.

Novoeight® is not used to treat von Willebrand Disease.

Important Safety Information

You should not use Novoeight® if you are allergic to factor VIII or any of the other ingredients of Novoeight® or if you are allergic to hamster proteins.

Call your healthcare provider right away and stop treatment if you get any of the following signs of an allergic reaction: rashes or hives, difficulty breathing or swallowing, tightness of the chest, swelling of the lips and tongue, light-headedness, dizziness or loss of consciousness, pale and cold skin, fast heartbeat, or red or swollen face or hands.

Before taking Novoeight®, you should tell your healthcare provider if you have or have had any medical conditions, take any medicines (including non-prescription medicines and dietary supplements), are nursing, pregnant or planning to become pregnant, or have been told that you have inhibitors to factor VIII.

Your body can make antibodies called “inhibitors” against Novoeight®, which may stop Novoeight® from working properly. Call your healthcare provider right away if your bleeding does not stop after taking Novoeight®.

Common side effects of Novoeight® include swelling or itching at the location of injection, changes in liver tests, and fever.

Please click here for Prescribing Information.

Novoeight® is a prescription medication.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800- FDA-1088.